Pharmacological Investigations on Vitexin

M. C. Prabhakar; H. Bano; I. Kumar; M. A. Shamsi; S. Y. Khan

doi:10.1055/s-2007-971532

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Planta Med 1981; 43(12): 396-403
DOI: 10.1055/s-2007-971532

Research Articles

Pharmacological Investigations on Vitexin

M. C. Prabhakar, H. Bano, I. Kumar, M. A. Shamsi, S. Y. Khan

Departments of Pharmacology and Medicinal Chemistry, Institute of History of Medicine and Medical Research, Hamdard Nagar, New Delhi, India

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Publication History

Publication Date:
30 March 2007 (online)

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Abstract

Vitexin (8-β-D-glucopyranosyl-apigenin) (VT), isolated from the flowers of Ochrocarpus longifolius L. and Arnebia hispidissima Dc., exhibited potent hypotensive, anti-inflammatory and anti-spasmodic (nonspecific) properties. Hypotensive effect of VT was attributed to its ganglion-blocking properties and antiinflammatory effects to its anti-histaminic, anti-bradykinin and anti-serotonin properties.

Key Word Index

Ochrocarpus longifolius - Arnebia hispidissima - Vitexin - Flavonoids - Hypotension - Anti-Inflammatory